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Thought disorder disrupts the flow of regular thinking and communication processes, causing widespread dysfunction that extends to emotions, behavior, and developing a sense of self.

People want, crave, and anticipate pleasure. To that end, dopamine is an excellent ingredient in a complex reward system. But dopamine as a "happiness hormone" is cutting the story short. Depending on dopamine receptors and the pathways followed in the brain, the neurotransmitter can act in a hellish world of delusion, hallucination, or permanent conditions that cause tremors or psychomotor dysfunction.

Yes, schizophrenia can be on a spectrum. As a matter of fact, a set of related disorders to schizophrenia make up the spectrum developed by the current medical community.